• EXTRACTION AND PHARMACOLOGICAL SCREENING OF CARVONE AND IT’S DERIVATIVES

Abstract

Phytoconstituents are responsible for many therapeutic activities. The aim of this research work is to separate the phytoconstituents, derivatization of phytoconstituents and its characterisation. And lastly compounds were evaluated for antioxidant and anticancer activity. The present work explains the antioxidant property of N-[(1 E)-2-methyl-5-(prop-1-en-2-yl) cyclohex-2-en-1-ylidene] methanamine obtained from caraway seeds (Carum carvi ).

The (1E)-1-[2-methyl-5-(prop-1-en-2-yl) cyclohex-2-en-1-ylidene]-2-phenyl hydrazine obtained from caraway seeds possess anticancer activity on MCF7 (breast), HeLa (cervix) and SK-OV3 (ovary) cell lines. This can prove as a new drug candidate for anticancer activity which can be explored further.