• IN VIVO CLINICAL STUDY OF SPIRULINA AS A ANTIDIABATIC

Priti Kumari, Shaheda Khanam, Manish Chandra Varma, Pritam Kumar, Asutosh K. Pandey*

Abstract


Alloxan induces irreversible diabetes mellitus after 24 hours following its administration and the condition proves to be chronic by laboratory tests after seven days. It interferes with cellular metabolic oxidative mechanisms. Intraperitoneal administration of streptozotocin (45 mg/kg) effectively induced diabetes in normal rats, as reflected by glycosuria, hyperglycemia, polyphagia, polydipsia and body weight loss when compared with normal rats. In the present study, it was observed and demonstrated that oral administration of Spirulina could reverse the above mentioned diabetic effects. Spirulina is used as medicine for the treatment of diabetes.


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