• DIURETIC ACTIVITY OF QUERCETIN ISOLATED FROM CANSJERA RHEEDII J.GMELIN (OPILIACEAE)

V. M. MOUNNISSAMY*

Abstract


Quercetin (3, 5, 7, 3’, 4’-Pentahydroxy flavone) isolated from the aerial parts of Cansjera rheedii J.Gmelin (Opiliaceae) has been tested for diuretic activity in rats.  The parameters observed for each individual rat included body weight before and after test period, total urine volume (corrected for water intake during the test period), urine concentration of Na+, K+ and Cl—. The values of urine volume and cation excretion were increased with reference to saline control by quercetin (100mg per kilogram of body weight).  Furesemide was used as a reference diuretic.


Keywords


Cansjera rheedii, Diuretic activity, Flavonoids, Caffeic acid, Ferulic acid, Quercetin, Quercetin-3-O-β-D- glucoside, Rutin, Furesemide.

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