• SYNTHESIS, CHARACTERIZATION AND EVALUATION OF ANTHELMINTIC ACTIVITY OF N-[2-(BENZOYLAMINO)-3-(PHENYL)-1-OXO-2-PROPENYL] ARGININE

Abstract

A synthetic arginine analogue N-[2-(benzoylamino)-3-(phenyl)-1-oxo-2-propenyl]arginine was synthesized using Azlactones,also called as 4-benzylidene-2-phenyl oxazol-5-ones which serves as an intermediate. Pheretima posthuma (Indian adult earth worms) were used for evaluating the anthelminthic activity. The purity of the synthesized compounds was evaluated by analytical methods such as TLC, UV and FT-IR. Time required for the paralysis and death of the earth worms was noted for each sample, by taking Piperazine citrate as the standard drug for comparing the results.